Raina MacIntyre is an international leader in emerging infections, and is involved in numerous face mask, vaccine, influenza and other infectious diseases research studies that directly inform national and international policy and practice in communicable disease control. Her research is underpinned by extensive field outbreak investigation experience. She is a graduate of the only Australian Field Epidemiology Training program, the MAE at ANU, and has extensive experience in shoe-leather epidemiology of infectious diseases outbreaks including influenza, meningococcal disease, clostridium perfringens, hepatitis A, legionella, mycoplasma, pertussis and gastroenteritis to name a few. Her in-depth understanding of the science of outbreak investigation draws from this experience combined with her academic training through a Masters and PhD in Epidemiology. Her passion for field epidemiology led her to co-found the ARM network for Australian outbreak response. She does research on the transmission dynamics and prevention of infectious diseases, particularly respiratory pathogens such as influenza, tuberculosis and other vaccine-preventable infections. She has also done research on using risk-analysis methods for analysing emerging infectious diseases outbreaks such as Ebola and MERS-CoV.
She leads a NHMRC Centre for Research Excellence in Epidemic Response which is international and multi-sectoral, and will address gaps in global systems for epidemic response. She won many career awards including the Sir Henry Wellcome Medal and Prize, from the Association of Military Surgeons of the United States in 2007 for her work on a risk-priority scoring system for category A bioterrorism agents; and the highest national award in infectious diseases, the Frank Fenner Award for Research in Infectious Diseases in 2003.
Awadh A, Chughtai AA, Dyda A, Sheikh M, Heslop DJ, MacIntyre CR. Does Zika Virus Cause Microcephaly – Applying the Bradford Hill Viewpoints. PLOS Currents Outbreaks. 2017 Feb 22 . Edition 1. doi: 10.1371/currents.outbreaks.2fced6e886074f6db162a00d4940133b.
Saha A;Rosewell A;Hayen A;MacIntyre CR;Qadri F, 2017, 'Improving immunization approaches to cholera', Expert Review of Vaccines, vol. 16, pp. 235 - 248, http://dx.doi.org/10.1080/14760584.2017.1249470, ROS ID: 853541
WONG ZS Y;BUI CM;CHUGHTAI AA;MACINTYRE CR, 2017, 'A systematic review of early modelling studies of Ebola virus disease in West Africa', Epidemiology and Infection, pp. 1 - 26, http://dx.doi.org/10.1017/S0950268817000164, ROS ID: 874683
Chughtai AA;Wang Q;Dung TC;Macintyre CR, 2017, 'The presence of fever in adults with influenza and other viral respiratory infections', Epidemiology and Infection, vol. 145, pp. 148 - 155, http://dx.doi.org/10.1017/S0950268816002181, ROS ID: 847567
Gardner, LM, Chughtai AA, MacIntyre CR. Risk of global spread of Middle East respiratory syndrome coronavirus (MERS-CoV) via the air transport network. Journal of Travel Medicine. DOI:http://dx.doi.org/10.1093/jtm/taw063 First published online: 5 September 2016
Bethmont A, Bui CM, Gardner L, Sarkar S, Chughtai AA, MacIntyre CR. Quantified degree of poultry exposure differs for human cases of avian influenza H5N1 and H7N9. Epidemiology and Infection 2016; 1-8. [Epub ahead of print]
Chughtai AA, Barnes M, MacIntyre CR. Persistence of Ebola virus in various body fluids during convalescence: evidence and implications for disease transmission and control. Epidemiol Infect.2016 Jan 25:1-9. [Epub ahead of print]
Bui CM, Gardner L, MacIntyre CR. Highly pathogenic avian influenza virus, Midwestern United States [letter]. Emerg Infect Dis. 2016 Jan. Vol. 22, number 1, 138-139. http://dx.doi.org/10.3201/eid2201.151053
Bui C, Rahman B, Heywood AE, MacIntyre CR. A Meta-Analysis of the Prevalence of Influenza A H5N1 and H7N9 Infection in Birds. Transbound Emerg Dis.2016 Jan 10. doi: 10.1111/tbed.12466. [Epub ahead of print]
MacIntyre CR, Chughtai AA. Recurrence and reinfection– a new paradigm for management of Ebola virus disease (EVD).Int J Infect Dis 2015; 43:58-61.
Zhang D, WuS, ZhangY, Yang P, MacIntyreCR, SealeH and *WangQ. Health literacy in Beijing: an assessment of adults’ knowledge and skills regarding communicable diseases. BMC Public Health2015, 15:799. doi:10.1186/s12889-015-2151-1
Heywood AE, Forssman BL, Seale H, MacIntyre CR, Zwar N. General Practitioners' Perception of Risk for Travelers Visiting Friends and Relatives. Journal of Travel Medicine, 2015.First published online: 15 JUL 2015. doi: 10.1111/jtm.12229
Chughtai AA, Rehman B, MacIntyre CR. Commentary on: Arriola et al. Antivirals and Effect Modification in Influenza Studies. Journal of Infectious Diseases, 2015. First published online: 14 JUL 2015. doi: 10.1093/infdis/jiv384
Ma T, Heywood A, MacIntyreCR. Chinese travellers visiting friends and relatives - A review of infectious risks. Travel Med Infect Dis.2015 May 14. pii: S1477-8939(15)00083-6. doi: 10.1016/j.tmaid.2015.05.004. [Epub ahead of print]
Zhang Y, Sun W, Svendsen ER, Tang S, MacIntyre CR, Yang P, Zhang D, *Wang Q. Do corticosteroids reduce the mortality of influenza A (H1N1) infection? A meta-analysis. Crit Care 2015;19(46):1-11. doi: 10.1186/s13054-015-0764-5. Epub 2015 Feb 20.
Wang X, Wu S, MacIntyre CR, Zhang H, Shi W, Peng X, et al. Using an Adjusted Serfling Regression Model to Improve the Early Warning at the Arrival of Peak Timing of Influenza in Beijing. PLoS ONE. 2015;10(3):e0119923.doi: 10.1371/journal.pone.0119923
*MacIntyre, CR, Travaglia, J. Heightened vulnerability, reduced oversight and ethical breaches on the Internet in the in West African Ebola epidemic. The American Journal of Bioethics, 2015.
Bui, C., A. Bethmont, A. A. Chughtai, L. Gardner, S. Sarkar, S. Hassan, H. Seale and C. R. MacIntyre, 2015: A Systematic Review of the Comparative Epidemiology of Avian and Human Influenza A H5N1 and H7N9 – Lessons and Unanswered Questions. Transboundary and Emerging Diseases, Jan 29, 2015. [Epub ahead of print]
Wood JG, Heywood AE, Menzies RI, McIntyre PB, MacIntyre CR. Predicting localised measles outbreak potential in Australia. Vaccine. 2015 Jan 22. [Epub ahead of print]
Hassan S, Kirk M, Stewart T, MacIntyre CR*. The ARM Network--a model for infectious disease surge response capacity in the Western Pacific Region. Western Pac Surveill Response J. 2014 Jun 16;5(2):5-8. doi: 10.5365/WPSAR.2014.5.2.011.
*MacIntyre CR. The discrepant epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV). Environ Syst Decis. 2014:1-8.
*Gardner LM and MacIntyreCR. Unanswered questions about the Middle East respiratory syndrome coronavirus (MERS-CoV). BMC Research Notes2014, 7:358 doi:10.1186/1756-0500-7-358
*Lauren M. Gardner, David Rey, Anita E. Heywood, Renin Toms, James Wood, S. Travis Waller, Mohamud Sheikh, C. Raina MacIntyre. A scenario-based evaluation of the Middle East respiratory syndrome coronavirus and the Hajj. Risk Analysis 2014;34(8):1391-400. .doi: 10.1111/risa.12253
*Muscatello DJ, Amin J, MacIntyre CR, Newall AT, Rawlinson WD, et al. (2014) Inaccurate Ascertainment of Morbidity and Mortality due to Influenza in Administrative Databases: A Population-Based Record Linkage Study. PLoS ONE 9(5): e98446.
*Muscatello DJ, Newall AT, Dwyer DE, MacIntyre CR. Mortality Attributable to Seasonal and Pandemic Influenza, Australia, 2003 to 2009, Using a Novel Time Series Smoothing Approach. PLoS ONE 2013; 8(6): e64734.
*Macintyre CR, Ridda I, Seale H, Gao Z, Ratnamohan VM, Donovan L, Zeng F, Dwyer DE. Respiratory viruses transmission from children to adults within a household. Vaccine. 30(19):3009-14, 2012 Apr 19.
*Macintyre CR, Burgess M, Isaacs D, McIntyre PB, Menzies R, Hull B. Epidemiology of severe hepatitis A in Indigenous Australian children. J Paediatr Child Health. 2007 May;43(5):383-387.
*Itzwerth RL, Macintyre CR, Shah S, Plant AJ. Pandemic influenza and critical infrastructure dependencies: possible impact on hospitals. Med J Aust. 2006 Nov 20;185(10):S70-S72.
*MacIntyre, CR; Goebel, K; Brown, GV. Patient knows best: blinded assessment of non-adherence with anti-tuberculous therapy by physicians, nurses and patients compared with urine drug levels. Preventive Medicine. 40(1):41-5, 2005.
*MacIntyre CR, McIntyre PB, Cagney M. Community based incidence and risk factors for all-cause childhood pneumonia in Western Sydney, Australia. Epi & Infection 2003;131:1091-6.
*MacIntyre CR, Hull B, Burgess MA, Gay NJ. Measles control in NSW Divisions of General Practice. NSW Public Health Bulletin. 2003; 14:13-17
*MacIntyre CR, Goebel K, Brown GV, Skull SA, Starr M, Fulinfaw RO. A randomised, controlled clinical trial of the efficacy of family based direct observation of anti-tuberculous therapy in an urban, developed-country setting. Int J Tuberc Lung Dis. 2003; 7(9):848-54
*MacIntyre CR, Gay NJ, Gidding H, Hull B, Gilbert GL, McIntyre P. A mathematical model to measure the impact of the Measles Control Campaign on the potential for measles transmission in Australia. Int J Infect Dis. 2002 Dec;6(4):277-81.
*MacIntyre CR. Empson M. Boardman C. Sindhusake D. Lokan J. Brown GV. Risk factors for colonization with vancomycin-resistant enterococci in a Melbourne hospital. Infection Control & Hospital Epidemiology. 22(10):624-9, 2001 October.
*MacIntyre CR. A case of uveitis associated with rifabutin in an HIV-negative patient with pulmonary Mycobacterium avium-intracellulare complex. Infectious Diseases In Clinical Practice 2000; Vol 9(8):pp 330-331.
*MacIntyre CR, Ansari MZ, Carnie J, Hart WG. No evidence for multiple drug prophylaxis for tuberculosis compared to isoniazid alone in South-East Asian refugees and migrants - completion and compliance are major determinants of effectiveness. Preventive Medicine. 2000; 30:425-432
*MacIntyre CR, Carnie J, Randall M. Risk of transmission of tuberculosis among inmates of an Australian prison. Epidemiology & Infection 1999;123:437-443.
*MacIntyre CR, Kendig N, Kummer L, Birago S, Plant AJ. Unrecognised transmission of tuberculosis in prisons. European Journal of Epidemiology 1999; 15:705-709.
*MacIntyre CR, Plant, AJ.Longitudinal incidence of tuberculosis in South-East Asian refugees after re-settlement. Int J Tuberc Lung Dis. 1999; 3:1-7.
*MacIntyre CR, Plant, AJ. Impact of policy and practice on the effectiveness of contact screening for tuberculosis. Preventive Medicine. 1998; 27: 830-837.
*MacIntyre CR, Plant, AJ. Preventability of incident cases of tuberculosis in recently exposed contacts. Int J Tuberc Lung Dis. 1998; 2:56-61.
*MacIntyre CR, Plant AJ. Tuberculosis in South-East Asian refugees - can prevention be improved by better policy and practice? Preventive Medicine. 1998; 27:815-820.
*MacIntyre CR, Plant AJ, Yung A, Streeton JA.Int J Tuberc Lung Dis Missed opportunities for prevention of tuberculosis (letter). 1998; 2:346-7.
*MacIntyre CR, Plant AJ, Yung A, Streeton JA.Int J Tuberc Lung Dis Missed opportunities for prevention of tuberculosis in Victoria, Australia. 1997; 1:135-41.
*MacIntyre CR, Kendig N, Kummer L, Birago S, Graham N. Impact of tuberculosis control measures and crowding on the incidence of tuberculosis infection in Maryland prisons. Clin Infect Dis 1997; 24:1060-1067. (Cited in Mandell, Douglas and Bennett's textbook of infectious diseases “Principles and Practice of Infectious Diseases, 5th edition, 2000)
*MacIntyre CR, Kendig N, Kummer L, Birago S, Graham NHM. Exposure to infectious tuberculosis in PPD skin test converters in Maryland prisons. Am J Respir Crit Care Med 1997; 155:A564.
*MacIntyre CR, Plant AJ, Hulls J, Streeton JA, Graham NMH, Rouch GJ. High rate of tuberculosis transmission in an office setting - impact of delayed diagnosis. Clinical Infectious Diseases. 1995; 21: 1170-4.
*MacIntyre R, Lehmann N, Leydon J. An outbreak of Mycoplasma pneumoniae infection in Victoria, 1992. Communicable Diseases Intelligence 1993; 17:32-5.
*MacIntyre R, Wilby R, Alter M, Brown R. An outbreak of gastroenteritis at a Melbourne Metropolitan Lifesaving Club. Communicable Diseases Intelligence 1993; 17:90-1.
*MacIntyre R, Murphy A, Taylor K. Meningococcal meningitis at a retirement village, Melbourne 1992 - Neisseria meningitidis carriage survey and prophylaxis of contacts. Communicable Diseases Intelligence 1993;17:287-288.
*MacIntyre R, Wilby R. An outbreak of Clostridium perfringens gastroenteritis at a Melbourne hospital, 1993. Communicable Diseases Intelligence 1993;17:257-259.
*MacIntyre R, Mansell C, Lynch P, Rich J. An outbreak of influenza A at a Victorian nursing home. Communicable Diseases Intelligence 1993;18:32-34.
*MacIntyre CR, Dwyer B, Streeton JA. The epidemiology of tuberculosis in Victoria. Medical Journal of Australia 1993;159: 672-677.